| Background: |
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. (The background information is obtained from official databases and does not represent the product information.) |
| Applications: |
ELISA, WB, IHC |
| Name of antibody: |
ACTB |
| Immunogen: |
Synthetic peptide of human ACTB |
| Full name: |
actin beta |
| Synonyms: |
BRWS1; PS1TP5BP1 |
| SwissProt: |
P60709 |
| ELISA Recommended dilution: |
5000-10000 |
| IHC positive control: |
Human tonsil |
| IHC Recommend dilution: |
50-100 |
| WB Predicted band size: |
42 kDa |
| WB Positive control: |
Mouse kidney tissue, Mouse brain tissue, 231 cell, Hela cell, 293T cell, HepG2 cell, NIH/3T3 cell lysates |
| WB Recommended dilution: |
1000-5000 |
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